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Monogenic causes of elevated HDL cholesterol and implications for development of new therapeutics
Identification of the CETP, LIPG (encoding endothelial lipase) and APOC3 genes, and ana lysis of rare genetic variants in them, have allowed researchers to increase understanding of HDL metabolism significantly. However, development of cardiovascular risk-reducing therapeutics targeting the proteins...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4217288/ https://ncbi.nlm.nih.gov/pubmed/25374625 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/clp.13.73 |
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