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RORγt and commensal microflora are required for the differentiation of mucosal interleukin 22–producing NKp46(+) cells

The mucosal immune system of the intestine is separated from a vast array of microbes by a single layer of epithelial cells. Cues from the commensal microflora are needed to maintain epithelial homeostasis, but the molecular and cellular identities of these cues are unclear. Here we provide evidence...

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Autores principales: Sanos, Stephanie L, Bui, Viet L, Mortha, Arthur, Oberle, Karin, Heners, Charlotte, Johner, Caroline, Diefenbach, Andreas
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4217274/
https://ncbi.nlm.nih.gov/pubmed/19029903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1684
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