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Enhanced murine antitumor immunity after genetic disruption of CD8(+) regulatory T-cell activity

Tumor growth is associated with the inhibition of host antitumor immune responses that can impose serious obstacles to cancer immunotherapy. To define the potential contribution of Qa-1-restricted CD8 regulatory T cells (Treg) to the development of tumor immunity, we studied B6.Qa-1 D227K mice that...

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Библиографические подробности
Главные авторы: Arias, Diana A. Alvarez, Kim, Hye-Jung, Zhou, Penghui, Holderried, Tobias A.W., Wang, Xuan, Dranoff, Glenn, Cantor, Harvey
Формат: Artigo
Язык:Inglês
Опубликовано: 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4217219/
https://ncbi.nlm.nih.gov/pubmed/24778317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-13-0121
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