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Associating disease-related genetic variants in intergenic regions to the genes they impact

We present a method to assist in interpretation of the functional impact of intergenic disease-associated SNPs that is not limited to search strategies proximal to the SNP. The method builds on two sources of external knowledge: the growing understanding of three-dimensional spatial relationships in...

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Autors principals: Macintyre, Geoff, Jimeno Yepes, Antonio, Ong, Cheng Soon, Verspoor, Karin
Format: Artigo
Idioma:Inglês
Publicat: PeerJ Inc. 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4217187/
https://ncbi.nlm.nih.gov/pubmed/25374782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.639
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