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Linking signaling pathways to transcriptional programs in breast cancer

Cancer cells acquire genetic and epigenetic alterations that often lead to dysregulation of oncogenic signal transduction pathways, which in turn alters downstream transcriptional programs. Numerous methods attempt to deduce aberrant signaling pathways in tumors from mRNA data alone, but these pathw...

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Detalhes bibliográficos
Publicado no:Genome Res
Main Authors: Osmanbeyoglu, Hatice U., Pelossof, Raphael, Bromberg, Jacqueline F., Leslie, Christina S.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4216927/
https://ncbi.nlm.nih.gov/pubmed/25183703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.173039.114
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