Widespread intron retention in mammals functionally tunes transcriptomes

Alternative splicing (AS) of precursor RNAs is responsible for greatly expanding the regulatory and functional capacity of eukaryotic genomes. Of the different classes of AS, intron retention (IR) is the least well understood. In plants and unicellular eukaryotes, IR is the most common form of AS, w...

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Hlavní autoři: Braunschweig, Ulrich, Barbosa-Morais, Nuno L., Pan, Qun, Nachman, Emil N., Alipanahi, Babak, Gonatopoulos-Pournatzis, Thomas, Frey, Brendan, Irimia, Manuel, Blencowe, Benjamin J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2014
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Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4216919/
https://ncbi.nlm.nih.gov/pubmed/25258385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.177790.114
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