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Glioblastoma cells inhibit astrocytic p53-expression favoring cancer malignancy

The tumor microenvironment has a dynamic and usually cancer-promoting function during all tumorigenic steps. Glioblastoma (GBM) is a fatal tumor of the central nervous system, in which a substantial number of non-tumoral infiltrated cells can be found. Astrocytes neighboring these tumor cells have a...

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Detalhes bibliográficos
Main Authors: Biasoli, D, Sobrinho, M F, da Fonseca, A C C, de Matos, D G, Romão, L, de Moraes Maciel, R, Rehen, S K, Moura-Neto, V, Borges, H L, Lima, F R S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4216902/
https://ncbi.nlm.nih.gov/pubmed/25329722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2014.36
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