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Identification of an Antigenic Determinant on the S2 Domain of the Severe Acute Respiratory Syndrome Coronavirus Spike Glycoprotein Capable of Inducing Neutralizing Antibodies

Severe acute respiratory syndrome (SARS) is a life-threatening disease caused by a newly identified coronavirus (CoV), SARS-CoV. The spike (S) glycoprotein of CoV is the major structural protein responsible for induction of host immune response and virus neutralization by antibodies. Hence, knowledg...

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Hlavní autoři: Zhang, Hong, Wang, Guangwen, Li, Jian, Nie, Yuchun, Shi, Xuanling, Lian, Gewei, Wang, Wei, Yin, Xiaolei, Zhao, Yang, Qu, Xiuxia, Ding, Mingxiao, Deng, Hongkui
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2004
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC421668/
https://ncbi.nlm.nih.gov/pubmed/15194770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.13.6938-6945.2004
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