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The urea decomposition product cyanate promotes endothelial dysfunction
The dramatic cardiovascular mortality of chronic kidney disease patients is attributable in a significant proportion to endothelial dysfunction. Cyanate, a reactive species in equilibrium with urea, is formed in excess in chronic kidney disease. Cyanate is thought to have a causal role in promoting...
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| Hauptverfasser: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4216595/ https://ncbi.nlm.nih.gov/pubmed/24940796 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2014.218 |
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