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Myeloperoxidase-derived chlorinating species induce protein carbamylation through decomposition of thiocyanate and urea: Novel pathways generating dysfunctional high-density lipoprotein
AIM: Protein carbamylation through cyanate is thought to have a causal role in promoting cardiovascular disease. We recently observed that the phagocyte protein myeloperoxidase (MPO) specifically induces high-density lipoprotein carbamylation, rather than chlorination, in human atherosclerotic lesio...
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Glavni autori: | , , , , , , , , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
2012
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Teme: | |
Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3810648/ https://ncbi.nlm.nih.gov/pubmed/22462773 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2011.4403 |
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