Differential response of epiblast stem cells to Nodal and Activin signalling: a paradigm of early endoderm development in the embryo

Mouse epiblast stem cells (EpiSCs) display temporal differences in the upregulation of Mixl1 expression during the initial steps of in vitro differentiation, which can be correlated with their propensity for endoderm differentiation. EpiSCs that upregulated Mixl1 rapidly during differentiation respo...

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Bibliografiske detaljer
Main Authors: Kaufman-Francis, Keren, Goh, Hwee Ngee, Kojima, Yoji, Studdert, Joshua B., Jones, Vanessa, Power, Melinda D., Wilkie, Emilie, Teber, Erdahl, Loebel, David A. F., Tam, Patrick P. L.
Format: Artigo
Sprog:Inglês
Udgivet: The Royal Society 2014
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4216471/
https://ncbi.nlm.nih.gov/pubmed/25349457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2013.0550
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