Hydrogel-Forming Microneedles Prepared from “Super Swelling” Polymers Combined with Lyophilised Wafers for Transdermal Drug Delivery

We describe, for the first time, hydrogel-forming microneedle arrays prepared from “super swelling” polymeric compositions. We produced a microneedle formulation with enhanced swelling capabilities from aqueous blends containing 20% w/w Gantrez S-97, 7.5% w/w PEG 10,000 and 3% w/w Na(2)CO(3) and uti...

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Hlavní autoři: Donnelly, Ryan F., McCrudden, Maelíosa T. C., Zaid Alkilani, Ahlam, Larrañeta, Eneko, McAlister, Emma, Courtenay, Aaron J., Kearney, Mary-Carmel, Singh, Thakur Raghu Raj, McCarthy, Helen O., Kett, Victoria L., Caffarel-Salvador, Ester, Al-Zahrani, Sharifa, Woolfson, A. David
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4216095/
https://ncbi.nlm.nih.gov/pubmed/25360806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0111547
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