Nicotine N-glucuronidation relative to N-oxidation and C-oxidation and UGT2B10 genotype in five ethnic/racial groups

Nicotine metabolism influences smoking behavior and differences in metabolism probably contribute to ethnic variability in lung cancer risk. We report here on the proportion of nicotine metabolism by cytochrome P450 2A6-catalyzed C-oxidation, UDP-glucuronosyl transferase 2B10 (UGT2B10)-catalyzed N-g...

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Autors principals: Murphy, Sharon E., Park, Sung-Shim L., Thompson, Elizabeth F., Wilkens, Lynne R., Patel, Yesha, Stram, Daniel O., Le Marchand, Loic
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
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Original Manuscript
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4216060/
https://ncbi.nlm.nih.gov/pubmed/25233931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgu191
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