The PmrA-Regulated pmrC Gene Mediates Phosphoethanolamine Modification of Lipid A and Polymyxin Resistance in Salmonella enterica

The PmrA/PmrB regulatory system of Salmonella enterica controls the modification of lipid A with aminoarabinose and phosphoethanolamine. The aminoarabinose modification is required for resistance to the antibiotic polymyxin B, as mutations of the PmrA-activated pbg operon or ugd gene result in strai...

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Detalhes bibliográficos

Publicado no:	J Bacteriol
Principais autores:	Lee, Hyunwoo, Hsu, Fong-Fu, Turk, John, Groisman, Eduardo A.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2004
Assuntos:	Molecular Biology of Pathogens
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC421605/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15205413/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JB.186.13.4124-4133.2004
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