Genetic and Functional Analysis of a PmrA-PmrB-Regulated Locus Necessary for Lipopolysaccharide Modification, Antimicrobial Peptide Resistance, and Oral Virulence of Salmonella enterica Serovar Typhimurium

The two-component regulatory system PmrA-PmrB confers resistance of Salmonella spp. to cationic antimicrobial peptides (AP) such as polymyxin (PM), bactericidal/permeability-increasing protein, and azurocidin. This resistance occurs by transcriptional activation of two loci termed pmrE and pmrHFIJKL...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Gunn, John S., Ryan, Sara S., Van Velkinburgh, Jennifer C., Ernst, Robert K., Miller, Samuel I.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Molecular and Cellular Pathogenesis
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97691/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11035717/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.11.6139-6146.2000
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