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Human Frataxin Activates Fe–S Cluster Biosynthesis by Facilitating Sulfur Transfer Chemistry

[Image: see text] Iron–sulfur clusters are ubiquitous protein cofactors with critical cellular functions. The mitochondrial Fe–S assembly complex, which consists of the cysteine desulfurase NFS1 and its accessory protein (ISD11), the Fe–S assembly protein (ISCU2), and frataxin (FXN), converts substr...

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Hlavní autoři: Bridwell-Rabb, Jennifer, Fox, Nicholas G., Tsai, Chi-Lin, Winn, Andrew M., Barondeau, David P.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2014
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215901/
https://ncbi.nlm.nih.gov/pubmed/24971490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi500532e
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