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Dose Schedule Optimization and the Pharmacokinetic Driver of Neutropenia
Toxicity often limits the utility of oncology drugs, and optimization of dose schedule represents one option for mitigation of this toxicity. Here we explore the schedule-dependency of neutropenia, a common dose-limiting toxicity. To this end, we analyze previously published mathematical models of n...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4215876/ https://ncbi.nlm.nih.gov/pubmed/25360756 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109892 |
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