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SGTA regulates the cytosolic quality control of hydrophobic substrates

Hydrophobic amino acids are normally shielded from the cytosol and their exposure is often used as an indicator of protein misfolding to enable the chaperone-mediated recognition and quality control of aberrant polypeptides. Mislocalised membrane proteins (MLPs) represent a particular challenge to c...

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Bibliografiska uppgifter
Huvudupphovsmän: Wunderley, Lydia, Leznicki, Pawel, Payapilly, Aishwarya, High, Stephen
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Company of Biologists 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215715/
https://ncbi.nlm.nih.gov/pubmed/25179605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.155648
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