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SGTA regulates the cytosolic quality control of hydrophobic substrates
Hydrophobic amino acids are normally shielded from the cytosol and their exposure is often used as an indicator of protein misfolding to enable the chaperone-mediated recognition and quality control of aberrant polypeptides. Mislocalised membrane proteins (MLPs) represent a particular challenge to c...
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| Main Authors: | , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Company of Biologists
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4215715/ https://ncbi.nlm.nih.gov/pubmed/25179605 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.155648 |
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