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Delivery of antisense oligodeoxyribonucleotides against the human epidermal growth factor receptor into cultured KB cells with liposomes conjugated to folate via polyethylene glycol.

Antisense oligodeoxyribonucleotides targeted to the epidermal growth factor (EGF) receptor were encapsulated into liposomes linked to folate via a polyethylene glycol spacer (folate-PEG-liposomes) and efficiently delivered into cultured KB cells via folate receptor-mediated endocytosis. The oligonuc...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Wang, S, Lee, R J, Cauchon, G, Gorenstein, D G, Low, P S
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42157/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7724560/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.8.3318
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