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Delivery of antisense oligodeoxyribonucleotides against the human epidermal growth factor receptor into cultured KB cells with liposomes conjugated to folate via polyethylene glycol.

Antisense oligodeoxyribonucleotides targeted to the epidermal growth factor (EGF) receptor were encapsulated into liposomes linked to folate via a polyethylene glycol spacer (folate-PEG-liposomes) and efficiently delivered into cultured KB cells via folate receptor-mediated endocytosis. The oligonuc...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Wang, S, Lee, R J, Cauchon, G, Gorenstein, D G, Low, P S
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1995
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42157/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7724560/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.8.3318
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