DNA polymerases engineered by directed evolution to incorporate non-standard nucleotides

DNA polymerases have evolved for billions of years to accept natural nucleoside triphosphate substrates with high fidelity and to exclude closely related structures, such as the analogous ribonucleoside triphosphates. However, polymerases that can accept unnatural nucleoside triphosphates are desire...

Full description

Saved in:
Bibliographic Details
Main Authors: Laos, Roberto, Thomson, J. Michael, Benner, Steven A.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2014
Subjects:
Microbiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215692/
https://ncbi.nlm.nih.gov/pubmed/25400626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2014.00565
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items