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DNA polymerases engineered by directed evolution to incorporate non-standard nucleotides
DNA polymerases have evolved for billions of years to accept natural nucleoside triphosphate substrates with high fidelity and to exclude closely related structures, such as the analogous ribonucleoside triphosphates. However, polymerases that can accept unnatural nucleoside triphosphates are desire...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Frontiers Media S.A.
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4215692/ https://ncbi.nlm.nih.gov/pubmed/25400626 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2014.00565 |
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