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DNA polymerases engineered by directed evolution to incorporate non-standard nucleotides

DNA polymerases have evolved for billions of years to accept natural nucleoside triphosphate substrates with high fidelity and to exclude closely related structures, such as the analogous ribonucleoside triphosphates. However, polymerases that can accept unnatural nucleoside triphosphates are desire...

詳細記述

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書誌詳細
主要な著者: Laos, Roberto, Thomson, J. Michael, Benner, Steven A.
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215692/
https://ncbi.nlm.nih.gov/pubmed/25400626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2014.00565
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