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Novel methylation specific real-time PCR test for the diagnosis of Klinefelter syndrome

The aim of this study was to design a molecular assay for the diagnosis of Klinefelter syndrome (KS), based on the detection of supernumerary X-chromosomes (X-chs). DNA was extracted from peripheral blood samples of twenty-six 47,XXY males; two 46,XY/47,XXY males; twenty-two 46,XY males; and 15 fema...

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Bibliographic Details
Main Authors: Mehta, Akanksha, Mielnik, Anna, Schlegel, Peter N, Paduch, Darius A
Format: Artigo
Language:Inglês
Published: Medknow Publications & Media Pvt Ltd 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215686/
https://ncbi.nlm.nih.gov/pubmed/24923458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1008-682X.125914
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