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Real-time methylation-specific PCR for the evaluation of methylation status of MGMT gene in glioblastoma

The methylation status of the O6-methylguanine-DNA methyltransferase (MGMT) gene is a strong predictor for the efficacy of temozolomide chemotherapy and survival periods. However, the correlation between the extent of methylation and the difference in survival times has not been fully clarified. Sim...

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Vydáno v:Oncotarget
Hlavní autoři: Yoshioka, Masaki, Matsutani, Tomoo, Hara, Ayaka, Hirono, Seiichiro, Hiwasa, Takaki, Takiguchi, Masaki, Iwadate, Yasuo
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6021237/
https://ncbi.nlm.nih.gov/pubmed/29963232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25543
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