Covalent modification of cytoskeletal proteins in neuronal cells by tryptamine-4,5-dione

Serotonin, 5-hydroxytryptamine, is a systemic bioactive amine that acts in the gut and brain. As a substrate of myeloperoxidase in vitro, serotonin is oxidized to tryptamine-4,5-dione (TD), which is highly reactive with thiols. In this work, we successively prepared a monoclonal antibody to quinone-...

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Autores principales: Kato, Yoji, Ono, Shigeki, Kitamoto, Noritoshi, Kettle, Anthony J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2014
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Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215393/
https://ncbi.nlm.nih.gov/pubmed/25460734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2014.08.004
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