MicroRNA-126 Suppresses Mesothelioma Malignancy by Targeting IRS1 and Interfering with the Mitochondrial Function

Aims: MiR126 was found to be frequently lost in many types of cancer, including malignant mesothelioma (MM), which represents one of the most challenging neoplastic diseases. In this study, we investigated the potential tumor suppressor function of MiR126 in MM cells. The effect of MiR126 was examin...

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Bibliographic Details
Main Authors: Tomasetti, Marco, Nocchi, Linda, Staffolani, Sara, Manzella, Nicola, Amati, Monica, Goodwin, Jacob, Kluckova, Katarina, Nguyen, Maria, Strafella, Elisabetta, Bajzikova, Martina, Peterka, Martin, Lettlova, Sandra, Truksa, Jaroslav, Lee, Wan, Dong, Lan-Feng, Santarelli, Lory, Neuzil, Jiri
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2014
Subjects:
Original Research Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215384/
https://ncbi.nlm.nih.gov/pubmed/24444362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2013.5215
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