MicroRNA-126 Suppresses Mesothelioma Malignancy by Targeting IRS1 and Interfering with the Mitochondrial Function

Aims: MiR126 was found to be frequently lost in many types of cancer, including malignant mesothelioma (MM), which represents one of the most challenging neoplastic diseases. In this study, we investigated the potential tumor suppressor function of MiR126 in MM cells. The effect of MiR126 was examin...

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Detalhes bibliográficos
Main Authors: Tomasetti, Marco, Nocchi, Linda, Staffolani, Sara, Manzella, Nicola, Amati, Monica, Goodwin, Jacob, Kluckova, Katarina, Nguyen, Maria, Strafella, Elisabetta, Bajzikova, Martina, Peterka, Martin, Lettlova, Sandra, Truksa, Jaroslav, Lee, Wan, Dong, Lan-Feng, Santarelli, Lory, Neuzil, Jiri
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2014
Assuntos:
Original Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215384/
https://ncbi.nlm.nih.gov/pubmed/24444362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2013.5215
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