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Postinduction serum infliximab trough level and decrease of C-reactive protein level are associated with durable sustained response to infliximab: a retrospective analysis of the ACCENT I trial

BACKGROUND: Serum infliximab trough levels correlate with efficacy; dose escalation is often beneficial in patients with Crohn's disease who stop responding to infliximab treatment. OBJECTIVE: To carry out a post hoc analysis of A Crohn's Disease Clinical Trial Evaluating Infliximab in a N...

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Detalhes bibliográficos
Main Authors: Cornillie, Freddy, Hanauer, Stephen B, Diamond, Robert H, Wang, Jianping, Tang, Kezhen L, Xu, Zhenhua, Rutgeerts, Paul, Vermeire, Séverine
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215276/
https://ncbi.nlm.nih.gov/pubmed/24474383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2012-304094
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