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Cytoplasmic Domain Interactions of Syndecan-1 and Syndecan-4 with α6β4 Integrin Mediate Human Epidermal Growth Factor Receptor (HER1 and HER2)-dependent Motility and Survival

Epithelial cells are highly dependent during wound healing and tumorigenesis on the α6β4 integrin and its association with receptor tyrosine kinases. Previous work showed that phosphorylation of the β4 subunit upon matrix engagement depends on the matrix receptor syndecan (Sdc)-1 engaging the cytopl...

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Detalhes bibliográficos
Main Authors: Wang, Haiyao, Jin, Haining, Beauvais, DeannaLee M., Rapraeger, Alan C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215216/
https://ncbi.nlm.nih.gov/pubmed/25202019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.586438
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