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Evolutionary Aspects of Enzyme Dynamics

The role of evolutionary pressure on the chemical step catalyzed by enzymes is somewhat enigmatic, in part because chemistry is not rate-limiting for many optimized systems. Herein, we present studies that examine various aspects of the evolutionary relationship between protein dynamics and the chem...

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Detalhes bibliográficos
Main Authors: Klinman, Judith P., Kohen, Amnon
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215204/
https://ncbi.nlm.nih.gov/pubmed/25210031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R114.565515
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