NF1 regulation of RAS/ERK signaling is required for appropriate granule neuron progenitor expansion and migration in cerebellar development

Cerebellar development is regulated by a coordinated spatiotemporal interplay between granule neuron progenitors (GNPs), Purkinje neurons, and glia. Abnormal development can trigger motor deficits, and more recent data indicate important roles in aspects of memory, behavior, and autism spectrum diso...

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Hlavní autoři: Sanchez-Ortiz, Efrain, Cho, Woosung, Nazarenko, Inga, Mo, Wei, Chen, Jian, Parada, Luis F.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2014
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215185/
https://ncbi.nlm.nih.gov/pubmed/25367036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.246603.114
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