Reconstitution of CPSF active in polyadenylation: recognition of the polyadenylation signal by WDR33

Cleavage and polyadenylation specificity factor (CPSF) is the central component of the 3′ processing machinery for polyadenylated mRNAs in metazoans: CPSF recognizes the polyadenylation signal AAUAAA, providing sequence specificity in both pre-mRNA cleavage and polyadenylation, and catalyzes pre-mRN...

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Главные авторы: Schönemann, Lars, Kühn, Uwe, Martin, Georges, Schäfer, Peter, Gruber, Andreas R., Keller, Walter, Zavolan, Mihaela, Wahle, Elmar
Формат: Artigo
Язык:Inglês
Опубликовано: Cold Spring Harbor Laboratory Press 2014
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Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215183/
https://ncbi.nlm.nih.gov/pubmed/25301781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.250985.114
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