MyD88 Is Dispensable for Cerebral Amyloidosis and Neuroinflammation in APP/PS1 Transgenic Mice

Activated microglia are associated with amyloid plaques in transgenic mouse models of cerebral amyloidosis and in human Alzheimer disease; yet, their implication in Alzheimer disease pathogenesis remains unclear. It has been suggested that microglia play dual roles depending on the context of activa...

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Bibliographic Details
Main Authors: Weitz, Tara M., Gate, David, Rezai-Zadeh, Kavon, Town, Terrence
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2014
Subjects:
Short Communication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215030/
https://ncbi.nlm.nih.gov/pubmed/25174876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2014.07.004
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