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Conserved active site cysteine residue of archaeal THI4 homolog is essential for thiamine biosynthesis in Haloferax volcanii

BACKGROUND: Thiamine (vitamin B1) is synthesized de novo by certain yeast, fungi, plants, protozoans, bacteria and archaea. The pathway of thiamine biosynthesis by archaea is poorly understood, particularly the route of sulfur relay to form the thiazole ring. Archaea harbor structural homologs of bo...

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Bibliografiset tiedot
Päätekijät: Hwang, Sungmin, Cordova, Bryan, Chavarria, Nikita, Elbanna, Dina, McHugh, Stephen, Rojas, Jenny, Pfeiffer, Friedhelm, Maupin-Furlow, Julie A
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215014/
https://ncbi.nlm.nih.gov/pubmed/25348237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12866-014-0260-0
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