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Antidepressants that inhibit both serotonin and norepinephrine reuptake impair long-term potentiation in hippocampus
RATIONALE: Monoamine reuptake inhibitors can stimulate expression of brain-derived neurotrophic factor (BDNF) and alter long-term potentiation (LTP), a widely used model for the synaptic mechanisms that underlie memory formation. BDNF expression is up-regulated during LTP, and BDNF in turn positivel...
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| Publicado no: | Psychopharmacology (Berl) |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4214920/ https://ncbi.nlm.nih.gov/pubmed/24781518 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-014-3587-1 |
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