Metabotropic glutamate receptor mGluR2/3 and mGluR5 binding in the anterior cingulate cortex in psychotic and nonpsychotic depression, bipolar disorder and schizophrenia: implications for novel mGluR-based therapeutics

BACKGROUND: Metabotropic glutamate receptors 2/3 (mGluR2/3) and 5 (mGluR5) are novel therapeutic targets for major depression (MD), bipolar disorder (BD) and schizophrenia. We aimed to determine whether mGluR2/3 and mGluR5 binding in the anterior cingulate cortex (ACC), a brain region essential for...

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Bibliographic Details
Published in:J Psychiatry Neurosci
Main Authors: Matosin, Natalie, Fernandez-Enright, Francesca, Frank, Elisabeth, Deng, Chao, Wong, Jenny, Huang, Xu-Feng, Newell, Kelly A.
Format: Artigo
Language:Inglês
Published: Canadian Medical Association 2014
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Research Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4214875/
https://ncbi.nlm.nih.gov/pubmed/24949866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1503/jpn.130242
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