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Addiction protein Phd of plasmid prophage P1 is a substrate of the ClpXP serine protease of Escherichia coli.

Plasmid-encoded addiction genes augment the apparent stability of various low copy number bacterial plasmids by selectively killing plasmid-free (cured) segregants or their progeny. The addiction module of plasmid prophage P1 consists of a pair of genes called phd and doc. Phd serves to prevent host...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Lehnherr, H, Yarmolinsky, M B
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 1995
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Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42148/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7724551/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.8.3274
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