Identification of a Novel Drug Lead That Inhibits HCV Infection and Cell-to-Cell Transmission by Targeting the HCV E2 Glycoprotein

Hepatitis C Virus (HCV) infects 200 million individuals worldwide. Although several FDA approved drugs targeting the HCV serine protease and polymerase have shown promising results, there is a need for better drugs that are effective in treating a broader range of HCV genotypes and subtypes without...

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محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Al Olaby, Reem R., Cocquerel, Laurence, Zemla, Adam, Saas, Laure, Dubuisson, Jean, Vielmetter, Jost, Marcotrigiano, Joseph, Khan, Abdul Ghafoor, Catalan, Felipe Vences, Perryman, Alexander L., Freundlich, Joel S., Forli, Stefano, Levy, Shoshana, Balhorn, Rod, Azzazy, Hassan M.
التنسيق: Artigo
اللغة:Inglês
منشور في: Public Library of Science 2014
الموضوعات:
Research Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC4214736/
https://ncbi.nlm.nih.gov/pubmed/25357246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0111333
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