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Notch3 Interactome Analysis Identified WWP2 as a Negative Regulator of Notch3 Signaling in Ovarian Cancer

The Notch3 signaling pathway is thought to play a critical role in cancer development, as evidenced by the Notch3 amplification and rearrangement observed in human cancers. However, the molecular mechanism by which Notch3 signaling contributes to tumorigenesis is largely unknown. In an effort to ide...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Jung, Jin-Gyoung, Stoeck, Alexander, Guan, Bin, Wu, Ren-Chin, Zhu, Heng, Blackshaw, Seth, Shih, Ie-Ming, Wang, Tian-Li
التنسيق: Artigo
اللغة:Inglês
منشور في: Public Library of Science 2014
الموضوعات:
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC4214668/
https://ncbi.nlm.nih.gov/pubmed/25356737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004751
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