Effects of MS-153 on chronic ethanol consumption and GLT1 modulation of glutamate levels in male alcohol-preferring rats

We have recently shown that upregulation of glutamate transporter 1 (GLT1) in the brain is associated in part with reduction in ethanol intake in alcohol-preferring (P) male rats. In this study, we investigated the effects of a synthetic compound, (R)-(−)-5-methyl-1-nicotinoyl-2-pyrazoline (MS-153),...

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Autori principali: Alhaddad, Hasan, Kim, Nathaniel T., Aal-Aaboda, Munaf, Althobaiti, Yusuf S., Leighton, James, Boddu, Sai H. S., Wei, Yangjie, Sari, Youssef
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2014
Soggetti:
Neuroscience
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4214358/
https://ncbi.nlm.nih.gov/pubmed/25400560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnbeh.2014.00366
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