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Effects of ceftriaxone on ethanol intake: a possible role for xCT and GLT-1 isoforms modulation of glutamate levels in P rats

RATIONALE: Evidence suggests that glutamate transporter 1 (GLT-1) and cystine/glutamate exchanger transporter (xCT) are critical in maintaining glutamate homeostasis. We have recently demonstrated that ceftriaxone treatment induced up-regulation of GLT1 levels and attenuated ethanol intake; however,...

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Autori principali: Alhaddad, Hasan, Das, Sujan C., Sari, Youssef
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176549/
https://ncbi.nlm.nih.gov/pubmed/24687412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-014-3545-y
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