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Thrombopoietin, the Mp1 ligand, is essential for full megakaryocyte development.

The development of megakaryocytes (MKs) from their marrow precursors is one of the least understood aspects of hematopoiesis. Current models suggest that early-acting MK colony-stimulating factors, such as interleukin (IL) 3 or c-kit ligand, are required for expansion of hematopoietic progenitors in...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Kaushansky, K, Broudy, V C, Lin, N, Jorgensen, M J, McCarty, J, Fox, N, Zucker-Franklin, D, Lofton-Day, C
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1995
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42140/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7536928/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.8.3234
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