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Thrombopoietin, the Mp1 ligand, is essential for full megakaryocyte development.

The development of megakaryocytes (MKs) from their marrow precursors is one of the least understood aspects of hematopoiesis. Current models suggest that early-acting MK colony-stimulating factors, such as interleukin (IL) 3 or c-kit ligand, are required for expansion of hematopoietic progenitors in...

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Bibliographic Details
Main Authors: Kaushansky, K, Broudy, V C, Lin, N, Jorgensen, M J, McCarty, J, Fox, N, Zucker-Franklin, D, Lofton-Day, C
Format: Artigo
Language:Inglês
Published: 1995
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC42140/
https://ncbi.nlm.nih.gov/pubmed/7536928
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