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Hormones and Diet, but Not Body Weight, Control Hypothalamic Microglial Activity

The arcuate nucleus (ARC) of the hypothalamus plays a key role in sensing metabolic feedback and regulating energy homeostasis. Recent studies revealed activation of microglia in mice with high-fat diet (HFD)-induced obesity (DIO), suggesting a potential pathophysiological role for inflammatory proc...

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Detalhes bibliográficos
Main Authors: Gao, Yuanqing, Ottaway, Nickki, Schriever, Sonja C., Legutko, Beata, García-Cáceres, Cristina, de la Fuente, Esther, Mergen, Clarita, Bour, Susanne, Thaler, Joshua P., Seeley, Randy J., Filosa, Jessica, Stern, Javier E., Perez-Tilve, Diego, Schwartz, Michael W., Tschöp, Matthias H., Yi, Chun-Xia
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4213950/
https://ncbi.nlm.nih.gov/pubmed/24166765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.22580
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