Extracellular ATP does not induce P2X7 receptor-dependent responses in cultured renal- and liver-derived swine macrophages

The P2X7 receptor (P2X7R) is an ATP-gated cation channel that is abundantly expressed in monocytes/macrophages. P2X7R activation by ATP results in various cellular responses including Ca(2+) influx, membrane pore formation, and cytokine secretion. Since P2X7R has low affinity for ATP, high concentra...

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Detalhes bibliográficos
Main Authors: Takenouchi, Takato, Suzuki, Shunichi, Shinkai, Hiroki, Tsukimoto, Mitsutoshi, Sato, Mitsuru, Uenishi, Hirohide, Kitani, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014
Assuntos:
Short Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4213840/
https://ncbi.nlm.nih.gov/pubmed/25379376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.rinim.2014.07.002
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