Critical Roles of the WASP N-Terminal Domain and Btk in LPS-Induced Inflammatory Response in Macrophages

While Wiskott-Aldrich syndrome protein (WASP) plays critical roles in TCR signaling as an adaptor molecule, how it transduces innate immune signals remains to be elucidated. To investigate the roles of WASP in innate immune cells, we established bone marrow-derived macrophage (BMDM) cell lines from...

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Bibliographic Details
Main Authors: Sakuma, Chisato, Sato, Mitsuru, Takenouchi, Takato, Chiba, Joe, Kitani, Hiroshi
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257260/
https://ncbi.nlm.nih.gov/pubmed/22253930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030351
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