Remodeling of Fibrous Extracellular Matrices by Contractile Cells: Predictions from Discrete Fiber Network Simulations

Contractile forces exerted on the surrounding extracellular matrix (ECM) lead to the alignment and stretching of constituent fibers within the vicinity of cells. As a consequence, the matrix reorganizes to form thick bundles of aligned fibers that enable force transmission over distances larger than...

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Autors principals: Abhilash, A.S., Baker, Brendon M., Trappmann, Britta, Chen, Christopher S., Shenoy, Vivek B.
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2014
Matèries:
Cell Biophysics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4213674/
https://ncbi.nlm.nih.gov/pubmed/25418164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.08.029
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