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Real-time observation of signal recognition particle binding to actively translating ribosomes
The signal recognition particle (SRP) directs translating ribosome-nascent chain complexes (RNCs) that display a signal sequence to protein translocation channels in target membranes. All previous work on the initial step of the targeting reaction, when SRP binds to RNCs, used stalled and non-transl...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4213662/ https://ncbi.nlm.nih.gov/pubmed/25358118 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.04418 |
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