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Signal Recognition Particle-ribosome Binding Is Sensitive to Nascent Chain Length

The signal recognition particle (SRP) directs ribosome-nascent chain complexes (RNCs) displaying signal sequences to protein translocation channels in the plasma membrane of prokaryotes and endoplasmic reticulum of eukaryotes. It was initially proposed that SRP binds the signal sequence when it emer...

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Détails bibliographiques
Auteurs principaux: Noriega, Thomas R., Tsai, Albert, Elvekrog, Margaret M., Petrov, Alexey, Neher, Saskia B., Chen, Jin, Bradshaw, Niels, Puglisi, Joseph D., Walter, Peter
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4094042/
https://ncbi.nlm.nih.gov/pubmed/24808175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.563239
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