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Signal Recognition Particle-ribosome Binding Is Sensitive to Nascent Chain Length

The signal recognition particle (SRP) directs ribosome-nascent chain complexes (RNCs) displaying signal sequences to protein translocation channels in the plasma membrane of prokaryotes and endoplasmic reticulum of eukaryotes. It was initially proposed that SRP binds the signal sequence when it emer...

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Detalhes bibliográficos
Main Authors: Noriega, Thomas R., Tsai, Albert, Elvekrog, Margaret M., Petrov, Alexey, Neher, Saskia B., Chen, Jin, Bradshaw, Niels, Puglisi, Joseph D., Walter, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4094042/
https://ncbi.nlm.nih.gov/pubmed/24808175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.563239
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