Pharmacokinetics and Efficacy of the Spleen Tyrosine Kinase Inhibitor R406 after Ocular Delivery for Retinoblastoma

PURPOSE: Retinoblastoma is a childhood cancer of the retina. Clinical trials have shown that local delivery of broad spectrum chemotherapeutic agents is efficacious. Recent studies characterizing the genomic and epigenomic landscape of retinoblastoma identified spleen tyrosine kinase (SYK) as a prom...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Pritchard, Eleanor M., Stewart, Elizabeth, Zhu, Fangyi, Bradley, Cori, Griffiths, Lyra, Yang, Lei, Suryadevara, Praveen Kumar, Zhang, Jiakun, Freeman, Burgess B., Guy, R. Kiplin, Dyer, Michael A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Springer US 2014
Aiheet:
Research Paper
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4213378/
https://ncbi.nlm.nih.gov/pubmed/24906597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-014-1399-y
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