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TGFβ Signaling Promotes Juvenile Granulosa Cell Tumorigenesis by Suppressing Apoptosis

Molecular changes that give rise to granulosa cell tumors of the ovary are not well understood. Previously, we showed that deletion in granulosa cells of the bone morphogenetic protein receptor-signaling transcription factors, Smad1 and Smad5, causes development of metastatic granulosa cell tumors t...

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Detalhes bibliográficos
Main Authors: Mansouri-Attia, Nadéra, Tripurani, Swamy K., Gokul, Nisha, Piard, Hermann, Anderson, Matthew L., Eldin, Karen, Pangas, Stephanie A.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4213364/
https://ncbi.nlm.nih.gov/pubmed/25243859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2014-1217
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