Therapeutic activity of an interleukin-4/interleukin-13 dual antagonist on oxazolone-induced colitis in mice

Interleukin-4 (IL-4) and IL-13 are critical drivers of immune activation and inflammation in ulcerative colitis, asthma and other diseases. Because these cytokines may have redundant function, dual targeting holds promise for achieving greater efficacy. We have recently described a bifunctional ther...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kasaian, Marion T, Page, Karen M, Fish, Susan, Brennan, Agnes, Cook, Timothy A, Moreira, Karen, Zhang, Melvin, Jesson, Michael, Marquette, Kimberly, Agostinelli, Rita, Lee, Julie, Williams, Cara M M, Tchistiakova, Lioudmila, Thakker, Paresh
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Blackwell Science Inc 2014
Pynciau:
Original Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4212955/
https://ncbi.nlm.nih.gov/pubmed/24831554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12319
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